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SAKAGUCHI Katsuhisa

Profile Research field Research achievement Educational achievement Social contribution achievement

 

Published Papers  
No.TitleJournalVolNoStart PageEnd PagePublication dateDOIReferee
1In-Vitro Decidualization With Different Progesterone Concentration: Development of a Hormone-Responsive 3D Endometrial Tissue Using Rat Endometrial Tissues Cureus Nov. 28, 2023 https://doi.org/10.7759/cureus.496131
2Titanium Culture Vessel Presenting Temperature Gradation for the Thermotolerance Estimation of Cells Cyborg and Bionic Systems Aug. 2023 https://doi.org/10.34133/cbsystems.00491
3Metallic Vessel with Mesh Culture Surface Fabricated Using Three-dimensional Printing Engineers Tissue Culture Environment Biotechnology and Bioprocess Engineering Jan. 30, 2023 https://doi.org/10.1007/s12257-022-0227-11Refereed 
4Production of scaffold-free cell-based meat using cell sheet technology npj Science of Food Sep. 3, 2022 https://doi.org/10.1038/s41538-022-00155-11Not refereed 
5Cell-Based Microfluidic Device Utilizing Cell Sheet Technology Cyborg and Bionic Systems 2022 Jan. 27, 2022 https://doi.org/10.34133/2022/97581871Refereed 
6Perfusable vascular tree like construction in 3D cell-dense tissues using artificial vascular bed Microvascular Research 141 104321 Jan. 2022 https://doi.org/10.1016/j.mvr.2022.1043211Refereed 
7In vitro ballooned hepatocytes can be produced by primary human hepatocytes and hepatic stellate cell sheets Scientific Reports 12 Dec. 2021 https://doi.org/10.1038/s41598-022-09428-x1Refereed 
8Bioengineering of a scaffold-less three-dimensional tissue using net mould Biofabrication 13 Sep. 6, 2021 https://doi.org/10.1088/1758-5090/ac23e31Refereed 
9Perfusable System Using Porous Collagen Gel Scaffold Actively Provides Fresh Culture Media to a Cultured 3D Tissue. International journal of molecular sciences 22 13 Jun. 24, 2021 https://doi.org/10.3390/ijms221367801Refereed 
10Functional Analysis of Induced Human Ballooned Hepatocytes in a Cell Sheet-Based Three Dimensional Model Tissue Engineering and Regenerative Medicine Jan. 30, 2021 https://doi.org/10.1007/s13770-020-00297-x1Refereed 
11Reconstruction of a Vascular Bed with Perfusable Blood Vessels Using a Decellularized Porcine Small Intestine for Clinical Application IFMBE Proceedings 284 292 2021 https://doi.org/10.1007/978-3-030-66169-4_351Refereed 
12Trends in Tissue Engineering and Cell Sheet Engineering Materials Science and Technology of Japan 57 172 175 Oct. 2020  Refereed 
13Measuring the Contractile Force of Multilayered Human Cardiac Cell Sheets. Tissue engineering. Part C, Methods 26 485 492 Sep. 2020 https://doi.org/10.1089/ten.TEC.2020.01641Refereed 
14Printing support hydrogels for creating vascular-like structures in stacked cell sheets Artificial Life and Robotics 25 199 203 May. 2020 https://doi.org/10.1007/s10015-020-00605-71Refereed 
15Microfluidic vascular-bed devices for vascularized 3D tissue engineering: tissue engineering on a chip Biomedical Microdevices 22 Mar. 2020 https://doi.org/10.1007/s10544-019-0461-21Refereed 
16In Vitro Production of Human Ballooned Hepatocytes in a Cell Sheet-based Three-dimensional Model. Tissue engineering. Part A 26 1-2 93 101 Jan. 2020 https://doi.org/10.1089/ten.TEA.2019.01011Refereed 
17Adequate taylor couette flow-mediated shear stress is useful for dissociating human iPS cell-derived cell aggregates. Regenerative therapy 12 13 Dec. 15, 2019 https://doi.org/10.1016/j.reth.2019.04.0061Refereed 
18Pulsatile tubular cardiac tissues fabricated by wrapping human iPS cells-derived cardiomyocyte sheets. Regenerative therapy 11 297 305 Dec. 2019 https://doi.org/10.1016/j.reth.2019.09.0011Refereed 
19Simple action potential measurement of cardiac cell sheet utilizing electronic sheet Artificial Life and Robotics 23 321 327 Sep. 2018 https://doi.org/10.1007/s10015-018-0429-y1Refereed 
20Low-temperature culturing improves survival rate of tissue-engineered cardiac cell sheets Biochemistry and Biophysics Reports 14 89 97 Jul. 2018 https://doi.org/10.1016/j.bbrep.2018.04.0011Refereed 
21Elucidation of the Relationship Between the Contractile Force and the Cross-sectional Area of Stacked human iPSC-derived Cardiomyocyte Sheets The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2018.30 2018 https://doi.org/10.1299/jsmebio.2018.30.2g121Refereed 
22Fundamental characteristics of printed gelatin utilizing micro 3D printer Artificial Life and Robotics 22 316 320 Sep. 1, 2017 https://doi.org/10.1007/s10015-016-0348-81Refereed 
23The potential of cell sheet technique on the development of hepatocellular carcinoma in rat models PLOS ONE 12 e0184004 Aug. 2017 https://doi.org/10.1371/journal.pone.01840041Refereed 
24Fabrication of micro-gelatin fiber utilizing coacervation method Artificial Life and Robotics 22 197 202 Jun. 1, 2017 https://doi.org/10.1007/s10015-016-0344-z1Refereed 
25Fabrication of micro-alginate gel tubes utilizing micro-gelatin fibers Japanese Journal of Applied Physics 56 May. 2017 https://doi.org/10.7567/JJAP.56.05EB061Refereed 
26Optical coherence microscopy of living cells and bioengineered tissue dynamics in high-resolution cross-section Journal of Biomedical Materials Research Part B - Applied Biomaterials 105 481 488 Apr. 2017 https://doi.org/10.1002/jbm.b.335661Refereed 
27Thicker three-dimensional tissue from a "symbiotic recycling system" combining mammalian cells and algae Scientific Reports 41594 Jan. 2017 https://doi.org/10.1038/srep415941Refereed 
28Vascularized Tissue-Engineered Model for Studying Drug Resistance in Neuroblastoma Theranostics 17 4099 4117 2017 https://doi.org/10.7150/thno.207301Refereed 
29Controlling sheer stress in a suspension culture using couette flow for efficient proliferation of HEK 293 cells Fluid Mechanics Open Access May. 2016 https://doi.org/10.4172/2476-2296.10001241Refereed 
30Spining of Micro gelatin fibers for fabrication of biodevices with cave Transactions of Japanese Society for Medical and Biological Engineering 54Annual 27PM-Abstract S165 S165 2016 https://doi.org/10.11239/jsmbe.54annual.s1651
31Controlling shape and position of vascular formation in engineered tissues by arbitrary assembly of endothelial cells Biofabrication 045006 Dec. 2015 https://doi.org/10.1088/1758-5090/7/4/0450061Refereed 
32Time Course of Cell Sheet Adhesion to Porcine Heart Tissue after Transplantation PLoS One 10 10 e0137494 Oct. 2015 https://doi.org/10.1371/journal.pone.01374941Refereed 
33Construction of three-dimensional vascularized cardiac tissue with cell sheet engineering Journal of Controlled Release 205 83 88 May. 2015 https://doi.org/10.1016/j.jconrel.2014.12.0161Refereed 
34In vitro engineering of vascularized tissue surrogates. Scientific reports 1316 1316 Feb. 2013 https://doi.org/10.1038/srep013161Refereed 
35In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels. Nature communications 1399 1399 Jan. 2013 https://doi.org/10.1038/ncomms24061Refereed 
36Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro. Nature protocols 850 Apr. 5, 2012 https://doi.org/10.1038/nprot.2012.0271Refereed 
37Novel device for transplantation of cell sheet and evaluation of thin polymer films by atomic force microscopy International Symposium on Micro-NanoMechatronics and Human Science 168 173 Nov. 2011 https://doi.org/10.1109/MHS.2011.61022011Refereed 
38Fabrication of Three-Dimensional Tissues with Perfused Microchannels IFMBE Proceedings 1213 1216 Nov. 2009 https://doi.org/10.1007/978-3-540-92841-6_2971Refereed 
39Development of Bioreactor System for Bioengineering Three-Dimensional Myocardial Tissues Journal of Life Support Technology 21 104 109 2009 https://doi.org/10.5136/lifesupport.21.1041Refereed 

 

MISC  
No.TitleJournalVolNoStart PageEnd PagePublication date
1Investigating optimum temperature for angiogenesis by the device giving multiple thermal doses 日本再生医療学会総会(Web) 22nd 2023 
2Evaluation of the efficacy of perfusion culture for the construction of three-dimensional endometrial-like tissue TISSUE ENGINEERING PART A 28 896 896 Oct. 2022 
3Development of rotary suspension culture method for cultured meat production 日本再生医療学会総会(Web) 21st 2022 
4Establishment of the Circular Cell Culture System with microalgae and mammalian cell 日本生物工学会大会講演要旨集 74th 2022 
5Study of Detecting Oral Disease Using Oral Images Acquired by a Dermoscope and Deep Learning 電子情報通信学会技術研究報告(Web) 122 188(MI2022 49-62) 2022 
6Transplantation of three-dimensional cardiac tissue by cell sheet rapid stacking 日本生物工学会大会講演要旨集 73rd 155 155 2021 
7Trends in Tissue Engineering and Cell Sheet Engineering 材料の科学と工学 57 172 175 Oct. 2020 
8Investigation into the effect of ovarian hormone to the thickness of human endometrial stromal cell sheets in vitro. 日本機械学会関東支部・精密工学会・茨城大学工学部茨城講演会講演論文集(CD-ROM) 28th 2020 
9Fabrication of gellan gum gels with unique shapes utilizing electrostatic inkjet. 日本機械学会関東支部・精密工学会・茨城大学工学部茨城講演会講演論文集(CD-ROM) 26th 2018 
10Fundamental characteristics of printing gellan gum ink utilizing electrostatic inkjet. 日本機械学会情報・知能・精密機器部門講演会論文集(CD-ROM) 2018 (Web) 2018 
11Fundamental study of algae co-culture method for three-dimentional fabrication 日本機械学会情報・知能・精密機器部門講演会論文集(CD-ROM) 2018 (Web) 2018 
12Fabrication of blood vessel-like structure in biological tissue using titanium wire 日本機械学会情報・知能・精密機器部門講演会論文集(CD-ROM) 2018 (Web) 2018 
13Rapid Fabrication of Tubular Tissue using Centrifuge 日本機械学会バイオフロンティア講演会講演論文集(CD-ROM) 29th 2018 
14Fabrication of 3-dimentional staked tissue for long-term hepatocytes culture 日本機械学会バイオフロンティア講演会講演論文集(CD-ROM) 29th 2018 
15Developing high precision patterning technology of biomaterial gels Imaging Conference Japan論文集 2017 13 16 2017 
163D Printing of Gelatin utilizing Micro 3D Printer Imaging Conference Japan論文集 2016 2016 
17H-3-2 Fabrication of micro gelatin fibers utilizing a PTFE mold Conference on Information, Intelligence and Precision Equipment : IIP 2016 "H 3-2-1"-"H-3-2-2" 2016 
18Construction of 3D Tissue by Cell Sheet Technology 日本画像学会誌 55 83 87 2016 
19Construction of Functional Liver Tissue Model by Cell Sheet Technology for Drug Test TISSUE ENGINEERING PART A 21 S264 S264 Sep. 2015 
20Engineering Vascularized Cardiac Tissue In Vitro TISSUE ENGINEERING PART A 21 S139 S139 Sep. 2015 
21Bioreactor technologies for myocardial tissue engineering Myocardial Tissue Engineering 211 220 Jan. 1, 2015 
22Induced Pluripotent Stem Cell Differentiation under Constant Shear Stress 7TH WACBE WORLD CONGRESS ON BIOENGINEERING 2015 52 10 2015 
23C212 Construction of Human Tissue Model with Microcirculation by Perfusion Culture in vitro The Proceedings of the JSME Conference on Frontiers in Bioengineering 26th 153 154 2015 
241E43 In vitro construction of three dimensional tissue with circulation system The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2014 159 160 2014 
25循環器系DRYラボセンターを駆使した治療リスクの低減システム構築と人材育成 左冠動脈主幹部分岐狭窄血管モデルを用いたステントの血管壁への不完全圧着領域評価方法の開発 循環器系DRYラボセンターを駆使した治療リスクの低減システム構築と人材育成に関する研究 平成25年度 総括・分担研究報告書 2014 
26移植へ向けた動静脈閉鎖系三次元ヒト組織の構築 再生医療 13 305 2014 
27ヒトIPS細胞由来心筋細胞シートへの灌流血管網導入技術の開発 日本バイオレオロジー学会年会プログラム・抄録集 37th 74 86 2014 
282S-Ep05 Fabrication of vascularized tissue by cell sheet engineering 日本生物工学会大会講演要旨集 66th 106 106 2014 
29Fabrication of Three-dimension Tissue by Cell Sheet Technology Bio industry 31 13 19 2014 
30組織移植へ向けた動静脈閉鎖系心筋組織の開発 再生医療 12 260 2013 
31Vascularized tissue fabrication from human cells using in vitro bioreactor JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 300 300 Sep. 2012 
32Engineering vascularized cardiac tissue in vitro JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 353 353 Sep. 2012 
33Fabrication of three-dimensional tubular cardiac tissue using neonatal mouse cardiomyocytes JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 354 354 Sep. 2012 
34移植可能な組織片開発へ向けた動静脈閉鎖系心筋組織構築 人工臓器(日本人工臓器学会) 41 S.113 113 2012 
357F44 The creation of a novel bioreactor for constructing microvascularized 3D tissue The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2012 _7F44 1_-_7F44-2_ 2012 
36Novel device for transplantation of cell sheet and evaluation of thin polymer films by atomic force microscopy 2011 Int. Symp. on Micro-NanoMechatronics and Human Science, Symp. on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "Hyper Bio Assembler for 3D Cellular System Innovation" 168 173 2012 
37生体外における動静脈閉鎖系心筋組織構築 再生医療 11 250 2012 
38厚い心筋組織構築に向けた血管導入技術の検討 人工臓器(日本人工臓器学会) 41 S.220 220 2012 
39微小流路付きコラーゲンゲル培養における血管網導入三次元心筋組織の構築 日本バイオマテリアル学会大会予稿集 33rd 187 187 Nov. 21, 2011 
40S021022 Fabrication of Vascularized Cardiac Tissue The Proceedings of Mechanical Engineering Congress, Japan 2011 _S021022 1-_S021022-5 2011 
41灌流培養における3次元心筋組織の構築 日本バイオレオロジー学会年会プログラム・抄録集 34th 85 104 2011 
42心筋細胞シートへの血管導入技術の開発 日本シミュレーション学会大会発表論文集 29th 221 224 Jun. 19, 2010 
43コラーゲンゲル内微小血管網の組織学的評価 再生医療 282 2010 
44Research on 3D tissue construction with blood vessels 再生医療 176 2010 
45“細胞から心臓を創る”~血管網導入技術の開発~ 人工臓器(日本人工臓器学会) 39 S.37 S37 2010 
460215 Fabrication of 3-dimensional tissue using human cells The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 22nd 2010 
47Development of Bioreactor System for Bioengineering Three-Dimensional Myocardial Tissues Journal of Life Support Engineering 21 104 109 Sep. 10, 2009 
48Fabrication of Three-Dimensional Tissues with Perfused Microchannels 13TH INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING, VOLS 1-3 23 1-3 1213 2009 
49微小流路付きコラーゲンゲル培養床に用いた三次元心筋組織構築の検討 人工臓器(日本人工臓器学会) 38 S.154 154 2009 
50三次元心筋組織構築のための微小流路付きコラーゲンゲル培養の検討 日本バイオマテリアル学会大会予稿集 31st 373 373 2009 
51Myocardial Tissue Engineering for Damaged Heart Repair 東京女子医科大学雑誌 79 108 112 2009 
52積層化細胞シートにおける酸素濃度解析 再生医療 234 2008 
53PE-530 Production of a Multilayer from Mesenchymal Stem Cell Sheets of Bone Marrow and Adipose Tissue of Pigs(Molecular biology, myocardium-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society) Circulation journal : official journal of the Japanese Circulation Society 71 456 457 Mar. 1, 2007 
54Development of the perfusion bioreactor to reconstruct 3-dimensional cardiac muscle tissues The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 16th 445 446 2004 

 

Awards & Honors  
No.Publication dateAssociationPrizeSubtitle
1Oct. 2023 Tissue Engineering and Regenerative Medicine International Society - Asia Pacific Best Poster Presentation Award (General) Fibrin-based myocardial sheet stacking generates three-dimensional cardiac tissue with high transplantation efficiency. 
2Jun. 2022 Outstanding Student Poster Presentation 
3Dec. 2021 TERMIS-AP Virtual Student Paper Contest Bronze Award Transplantation of layered cell sheet into myocardial infarction model rat 
4May. 2020 The 11th Asian Pacific Conference on Medical and Biological Engineering The First Prize Award for the IFMBE-Sponsored Young Investigator Award Reconstruction of a vascular bed with perfusable blood vessels using a decellularized porcine small intestine for clinical application 
5Sep. 2018 5th TERMIS World Congress SYIS Oral Presentation Award Fabrication of a human implantable vascular bed using decellularized porcine small intestine re-endothelialized with human cells 
6Dec. 2017 Outstanding Poster Presentation 
7Jun. 2017 The 2nd International Symposium on Bio-Therapeutics Delivery Best Poster Award Shrinkage of hepatocyte sheet can preserve liver-specific functions 
8Nov. 2010 International Symposium of Materials on Regenerative Medicine Excellent Poster Award Construction of Vascularized Cardiac Tissue in a Bioreactor 
9Dec. 2008 International Conference on Biomechanics and Medical Engineering Outstanding Paper Award Fabrication of Three-Dimensional Tissues with Perfused Microchannels 

 

Research Grants & Projects  
No.Offer organizationSystem nameTitleFund classificationDate
1Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C) Development of the Dermatoscope for the oral cavity and establish of the new diagnostic method of oral mucosa disease using the artificial intelligence technology  Apr. 2021 - Mar. 2024 
2Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Challenging Research (Exploratory) Development of a minimally invasive electronic sheet for ex vivo monitoring of artificial cardiomyocyte tissue  Jul. 2020 - Mar. 2022 
3Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B) Real-time quantitative prediction of cerebral-aneurysm growth with thrombosis-stratified vascular remodeling  Apr. 2019 - Mar. 2022 
4Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C) Development of high-speed cell sheet stacking method to achieve high transplantation efficiency  Apr. 2019 - Mar. 2022 
5Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Challenging Research (Exploratory) Development of Smart Electronics Sheet Within Cardiac Cell Sheet  Jun. 2018 - Mar. 2020 
6Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B) Controlling sheer stress in a suspension culture using qouette flow for efficient cell proliferation  Apr. 2017 - Mar. 2019 
7Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research 3D Cell Structure Utilizing Micro 3D Printer and Cell Sheet  Apr. 2016 - Mar. 2018 
8Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B) Development of a tissue with in vivo regeneration capability for reconstruction of anterior cruciate ligament using decellularization and tissue-sterilization technologies  Apr. 2014 - Mar. 2017 
9Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area) Fabrication of structually comlicated soft tissue such as liver-tissues and understanding its biological function of teh fabricated liver-tissue  Apr. 2011 - Mar. 2016